DNA encoding N.gradient.2 CSF-1 (short form) and carboxy truncated fragment thereof
US6204020A · kind A · utility
8Cited by
19References
10Claims
0Family size
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Key dates
| Filing date | Mar 9, 1995 |
| Grant date | Mar 20, 2001 |
| Priority date | — |
| Expiry date | Mar 9, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/145
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A colony stimulating factor, CSF-1, is a lymphokine useful in regulating the immune system, is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein. Both "long" and "short" forms of this protein and muteins corresponding to the cDNA-encoded forms are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.