Conjugate vaccine for nontypeable Haemophilus influenzae

US6207157A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Xin Gu · San Francisco, US
• Chao-Ming Tsai · Bethesda, US
• David J. Lim · Pasadena, US
• John B. Robbins · New York, US

Key dates

• Filing date: Apr 23, 1997
• Grant date: Mar 27, 2001
• Expiry date: Apr 23, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/851
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A conjugate vaccine for Nontypeable Haemophilus influenzae comprising lipooligosaccharide from which esterified fatty acids have been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of otitis media and respiratory infections in mammals.