Patent · US Expired

Method for producing optically active compound

US6207427A · kind A · utility

25Cited by
6References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 5, 1998
Grant dateMar 27, 2001
Priority date
Expiry dateJun 5, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P7/46
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides a method for industrially advantageously producing (S)-4-hydroxy-2-ketoglutaric acid and for producing compounds which are formed by biosynthesis from the precursor (S)-4-hydroxy-2-ketoglutaric acid, for example, for producing the compounds (2S,4S)-4-hydroxy-L-glutamic acid and (2S,4S)-4-hydroxy-L-proline, using a recombinant microorganism carrying a recombinant DNA harboring the DNA fragment encoding 4(S)-4-hydroxy-2-ketoglutaric acid aldolase gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.