Transgenic coagulation factor XIII defective animal and its use for testing wound healing and bleeding

US6207877A · kind A · utility

Assignee

• Aventis Behring GmbH · DE

Inventors

• Gerhard Dickneite · Marburg, DE
• Hubert Metzner · Marburg, DE
• Gerd Zettlmeissl · Lahntal, DE
• Ulrich Grundmann · Lahntal, DE
• Richard Lathe · Edinburgh, GB
• Austin Gerard Smith · Edinburgh, GB
• Meng Li · Edinburgh, GB

Key dates

• Filing date: Sep 23, 1999
• Grant date: Mar 27, 2001
• Expiry date: Sep 23, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A01K2267/0306
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a transgenic mouse which is heterozygous or homozygous for an at least partially defective coagulation factor XIII gene.