Inventor · Marburg, DE

Hubert Metzner

28Patents
9h-index
33Co-inventors
75Inventor score

Filing activity: Dec 22, 1997 → Dec 2, 2020

Most-cited inventions

PatentTitleAreaCited byStatus
US7045601B2 Storage-stable, liquid fibrinogen formulation Human Necessities 37 Expired
US7276235B2 Tissue glue with improved antiadhesive properties Human Necessities 32 Expired
US6874657B2 Biological sealant storage and dispensing system Human Necessities 31 Expired
US7939632B2 Proteolytically cleavable fusion proteins with high molar specific activity Chemistry; Metallurgy 26 Active
US6447774B1 Stabilized protein preparations for a tissue adhesive Human Necessities 16 Expired
US8575104B2 Factor VIII, von willebrand factor or complexes thereof with prolonged in vivo half-life Chemistry; Metallurgy 14 Active
US7351561B2 Thrombin preparations and process for their production Human Necessities 13 Expired
US6204036A Stable transglutaminase preparations and processes for their production Human Necessities 10 Expired
US6790410B2 Use of a hydrogen peroxide plasma sterilization method for the mild sterilization of temperature-sensitive products Human Necessities 10 Expired
US7550567B2 Fibrinogen purification Human Necessities 9 Expired
US8754194B2 Modified coagulation factors with prolonged in vivo half-life Chemistry; Metallurgy 9 Active
US7939288B2 Method for differentiating between factor XIII deficiency states and fibrinogen deficiency states by means of thrombelastographic techniques Chemistry; Metallurgy 6 Active
US9956269B2 Method for improving the stability of purified factor VIII after reconstitution Chemistry; Metallurgy 4 Active
US10537616B2 Method for improving the stability of purified factor VIII after reconstitution Chemistry; Metallurgy 4 Active
US9394353B2 Method for improving the stability of purified factor VIII after reconstitution Chemistry; Metallurgy 3 Active
US10881717B2 Method for improving the stability of purified Factor VIII after reconstitution Chemistry; Metallurgy 3 Active
US9878017B2 Covalent complex of von Willebrand Factor and factor VIII, compositions, and uses relating thereto Chemistry; Metallurgy 2 Active
US9290561B2 Factor VIII, von Willebrand factor or complexes thereof with prolonged in vivo half-life Chemistry; Metallurgy 1 Active
US10688157B2 Truncated von Willebrand factor polypeptides for treating hemophilia Human Necessities 1 Active
US8012728B2 Thrombin preparations and process for their production Human Necessities 1 Active
US11510968B2 Method for improving the stability of purified Factor VIII after reconstitution Chemistry; Metallurgy 0 Active
US9511123B2 Combined use of a sulfated glycosaminoglycan and a hyaluronidase for improving the bioavailability of factor VIII Chemistry; Metallurgy 0 Active
US10238718B2 Factor VIII formulation Human Necessities 0 Active
US11814421B2 Truncated von Willebrand Factor polypeptides for treating hemophilia Chemistry; Metallurgy 0 Active
US11479578B2 Protein purification and virus inactivation with alkyl glycosides Human Necessities 0 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.