System for detecting nucleic acid hybridization, preparation method and application thereof
US6210932A · kind A · utility
1Cited by
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15Claims
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Key dates
| Filing date | Dec 3, 1999 |
| Grant date | Apr 3, 2001 |
| Priority date | — |
| Expiry date | Dec 3, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention concerns nucleic acid detection using a probe consisting of: a binding domain A, consisting of a single strand polynucleotide; and intermediate domain B, consisting of at least a stop synthon; and a display domain C, consisting of a double strand polynucleotide, wherein is incorporated at least a marked nucleotide constituting detection means. The use of said probes amplifies the hybridisation signal with nucleic acid target sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.