Enhancement of musculature in non-human mammals expressing c-ski
US6218596A · kind A · utility
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1References
13Claims
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Assignee
Inventors
Key dates
| Filing date | Feb 23, 1994 |
| Grant date | Apr 17, 2001 |
| Priority date | — |
| Expiry date | Feb 23, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to DNA segments encoding chicken c-ski protein, to DNA constructs comprising the DNA segments and to cells transformed therewith. The present invention further relates to non-human transgenic mammals having increased muscle size and/or reduced fat. In addition, the present invention relates to methods of stimulating muscle growth and preventing degeneration of muscle, and to methods of treating muscle degenerative diseases and obesity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.