Method of selection for genes encoding secreted and transmembrane proteins
US6228590A · kind A · utility
8Cited by
12References
29Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 19, 1999 |
| Grant date | May 8, 2001 |
| Priority date | — |
| Expiry date | Mar 19, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/865
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a novel, improved method of identifying cDNA's which encode secreted and membrane-bound proteins. The methods of the invention provide for an improved signal sequence detection system using host strains deficient in post-translation translocation of siren sequences, which results in a greater number of correctly identified signal sequences and less total time required to complete the procedure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.