N-aroylphenylalanine derivative VCAM-1 inhibitors
US6229011A · kind A · utility
41Cited by
4References
308Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 21, 1998 |
| Grant date | May 8, 2001 |
| Priority date | — |
| Expiry date | Aug 21, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula: ##STR1## are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expressing VLA-4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.