Patent · US Expired

Method for treating brain cancer with a conditionally lethal gene

US6241982A · kind A · utility

5Cited by
21References
34Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 1995
Grant dateJun 5, 2001
Priority date
Expiry dateJun 6, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2840/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides recombinant viral vectors carrying a vector construct which directs the expression of a gene product (e.g., HSVTK) that activates a compound with little or no cytotoxicity into a toxic product. Also provided are methods of destroying or inhibiting pathogenic agents in a warm blooded animal, comprising the step of administering to the animal a viral vector such as that described above, in order to inhibit or destroy the pathogenic agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.