Polycationic polymers
US6251433A · kind A · utility
16Cited by
5References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 13, 1997 |
| Grant date | Jun 26, 2001 |
| Priority date | — |
| Expiry date | Aug 13, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/858
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates compositions and methods for increasing the uptake of polynucleotides into cells. Specifically, the invention relates to vectors, targeting ligands, and polycationic agents. The polycationic agents are capable of (1) increasing the frequency of uptake of polynucleotides into a cell, (2) condensing polynucleotides; and (3) inhibiting serum and/or nuclease degradation of polynucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.