Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these antibodies

US6252052A · kind A · utility

Assignees

• Cornell Research Foundation, Inc. · US
• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB
• Memorial Sloan Kettering Cancer Center · US

Inventors

• Elisabeth Stockert · New York, US
• Elke Jager · Frankfurt am Main, DE
• Yao-Tseng Chen · New York, US
• Matthew Scanlan · Princeton Junction, US
• Knuth Alexander · Frankfurt am Main, DE
• Lloyd J. Old · New York, US

Key dates

• Filing date: Apr 17, 1998
• Grant date: Jun 26, 2001
• Expiry date: Apr 17, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also described are truncated, recombinant forms of the cancer associated antigen.