Patent · US Expired

Pharmaceutical composition

US6255284A · kind A · utility

15Cited by
26References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 11, 2000
Grant dateJul 3, 2001
Priority date—
Expiry dateFeb 11, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Polypeptide pharmaceutical compositions having improved stability and resistance to aggregation, particle formation and precipitation comprising a polypeptide pharmaceutical and poloxamer surfactants alone, or in combination with polysorbate surfactants. Preferred polypeptides stabilized are bactericidal/permeability increasing (BPI) protein, biologically active fragments of BPI, biologically active analogs of BPI, and biologically active variants of BPI.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.