Indazole derivatives and their use as inhibitors of phosphodiesterase (PDE) type IV and the production of tumor necrosis factor (TNF)
US6262040A · kind A · utility
16Cited by
5References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 4, 1999 |
| Grant date | Jul 17, 2001 |
| Priority date | — |
| Expiry date | Mar 4, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R, R.sub.1, and R.sub.2, are as defined herein. The invention further relates to pharmaceutical compositions containing, and methods of using, the compounds of formula (I), or acceptable salts thereof, for the inhibition of phosphodiesterase (PDE) type IV or the production of tumor necrosis factor (TNF) in a mammal. The invention also relates to intermediates that are useful in the preparation of the compounds of formula (I). ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.