Method and product for the sequence determination of peptides using a mass spectrometer

US6271037A · kind A · utility

Assignees

• The Rockefeller University · US
• THE SCRIPPS RESEARCH INSTITUTE · US

Inventors

• Brian T. Chait · New York, US
• Ronald Beavis · Winnipeg, CA
• Rong Wang · Mianyang, CN
• Stephen B. H. Kent · Melbourne, AU

Key dates

• Filing date: Jun 24, 1996
• Grant date: Aug 7, 2001
• Expiry date: Jun 24, 2016

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/255
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Method is described for sequencing polypeptides by forming peptide ladders comprising a series of polypeptides in which adjacent members of the series vary by one amino acid residue and determining the identity and position of each amino acid in the polypeptide by mass spectroscopy.