Constrained helical peptides and methods of making same
US6271198A · kind A · utility
74Cited by
4References
4Claims
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Key dates
| Filing date | Nov 5, 1997 |
| Grant date | Aug 7, 2001 |
| Priority date | — |
| Expiry date | Nov 5, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are cyclized peptides with a constrained region(s) having an .alpha.-helical conformation. Constrained helical peptides having amino acid sequences from HIV gp41 are provided, as is their use in preparing antibodies that prevent viral membrane fusion. Also provided are methods for making such cyclized peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.