Chimeric molecules targeted to viral RNAs

US6271369A · kind A · utility

Assignees

• The United States of America, as represented by the Department of Health and Human Services · US
• The Cleveland Clinic Foundation · US

Inventors

• Paul F. Torrence · Gaithersburg, US
• Robert H. Silverman · Shaker Heights, US
• Ratan Maitra · Euclid, US
• Krystyna Lesiak · Gaithersburg, US

Key dates

• Filing date: Oct 14, 1997
• Grant date: Aug 7, 2001
• Expiry date: Oct 14, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/143333
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Chimeric molecules comprising a virus targeting antisense oligonucleotide moiety attached to an activator of 2-5A-dependent RNase.