Chemical synthesis apparatus employing a droplet generator

US6277334A · kind A · utility

Assignee

• Isis Pharmaceuticals, Inc. · US

Inventors

• David J. Ecker · Encinitas, US
• Oscar L. Acevedo · San Diego, US
• Normand Hebert · Irvine, US
• Peter Davis · Carlsbad, US
• Jacqueline Wyatt · Carlsbad, US
• John S. Kiely · San Diego, US

Key dates

• Filing date: May 18, 1999
• Grant date: Aug 21, 2001
• Expiry date: May 18, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B60/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Chemical reaction apparatus, materials and methods are provided for the automatable, efficient synthesis of chemical species and libraries. In accordance with preferred embodiments, chemical droplet generation and direction techniques are employed to prepare oligomers and libraries of chemical species. Reaction assemblies adapted for efficient synthetic employment and for improved collection are also disclosed.