Biarylalkanoic acids as cell adhesion inhibitors
US6291511A · kind A · utility
21Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1999 |
| Grant date | Sep 18, 2001 |
| Priority date | — |
| Expiry date | Jul 22, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of Formula I are antagonists of VLA-4 and/or .alpha..sub.4.beta..sub.7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma, allergies, inflammation, multiple sclerosis, and other inflammatory and autoimmune disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.