Diagnostic method for Alzheimer's disease
US6300085A · kind A · utility
13Cited by
2References
13Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 18, 1997 |
| Grant date | Oct 9, 2001 |
| Priority date | — |
| Expiry date | Jul 18, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods for the diagnosis of Alzheimer's disease using human cells. Specifically, one method detects differences between potassium channels in cells from Alzheimer's patient and normal donors, and differences in intracellular calcium concentrations between Alzheimer's and normal cells in response to chemicals known to increase intracellular calcium levels. Other methods detect differences between the memory associated GTP binding Cp20 protein levels between Alzheimer's and normal cells. In addition a diagnostic index for improved assessment between Alzheimer's and non Alzheimer's cells is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.