Sugar modified oligonucleotides that detect and modulate gene expression
US6307040A · kind A · utility
125Cited by
15References
8Claims
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Key dates
| Filing date | Sep 23, 1997 |
| Grant date | Oct 23, 2001 |
| Priority date | — |
| Expiry date | Sep 23, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compositions and methods are provided for the treatment and diagnosis of diseases amenable to modulation of the production of selected proteins. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the 2'-deoxyfuranosyl moieties of the nucleoside unit is modified. Treatment of HIV, herpes virus, papillomavirus and other infections is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.