Aralkyl diazabicycloalkane derivatives for CNS disorders

US6310064A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Wayne Bowen · Derwood, US
• Brian R. de Costa · Rockville, US
• Celia Dominguez · Los Angeles, US
• Xiao He · Branford, US
• Kenner C. Rice · Bethesda, US

Key dates

• Filing date: Jul 6, 1999
• Grant date: Oct 30, 2001
• Expiry date: Jul 6, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Certain aralkyl diazabicycloalkyl compounds are disclosed for treatment of CNS disorders, such as cerebral ischemia, psychosis, and convulsions. For example, compounds of interest are of the formula: ##STR1##