Partial intron sequence of von hippel-lindau (VHL) disease gene and its use in diagnosis of disease

US6312890A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• W. Marston Linehan · Bethesda, US
• Michael Lerman · Rockville, US
• Farida Latif · Birmingham, GB
• Berton Zbar · Garrett Park, US

Key dates

• Filing date: Mar 28, 1996
• Grant date: Nov 6, 2001
• Expiry date: Mar 28, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The Von Hippel-Lindau (VHL) disease gene and its corresponding cDNA are disclosed. Methods for detecting carriers of the VHL disease gene using probes derived from the VHL disease gene sequence are described. Pharmaceutical compositions and methods of treating diseases related to the VHL gene are also disclosed.