Anti-viral guanosine-rich oligonucleotides and method of treating HIV
US6323185A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1996 |
| Grant date | Nov 27, 2001 |
| Priority date | — |
| Expiry date | Jul 17, 2016 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01L2924/0002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and compositions for treating viral infection in vitro and in vivo using a guanosine-rich oligonucleotide. The oligonucleotides have sufficient guanosine to form a guanosine tetrad. Also provided are oligonucleotides of at least two runs of at least two guanosines. Also provided are guanosine-rich oligonucleotides and methods for treating viral infections in humans, and a method for designing guanosine-rich oligonucleotides having anti-viral activity and integrase inhibition activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.