Patent · US Expired

Anti-viral guanosine-rich oligonucleotides and method of treating HIV

US6323185A · kind A · utility

5Cited by
13References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 17, 1996
Grant dateNov 27, 2001
Priority date
Expiry dateJul 17, 2016

Classification

  • Technology area (CPC H)Electricity
  • CPC primaryH01L2924/0002
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method and compositions for treating viral infection in vitro and in vivo using a guanosine-rich oligonucleotide. The oligonucleotides have sufficient guanosine to form a guanosine tetrad. Also provided are oligonucleotides of at least two runs of at least two guanosines. Also provided are guanosine-rich oligonucleotides and methods for treating viral infections in humans, and a method for designing guanosine-rich oligonucleotides having anti-viral activity and integrase inhibition activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.