Manganese superoxide dismutase cloning and expression in microorganisms
US6326003A · kind A · utility
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6Claims
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Key dates
| Filing date | Oct 14, 1986 |
| Grant date | Dec 4, 2001 |
| Priority date | — |
| Expiry date | Oct 14, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for the production of human manganese superoxide dismutase and a protocol for enhancing efficiency of expression. The gene encoding for human manganese superoxide dismutase was isolated and inserted into a vector in conjunction with a synthetic linker which provides for enhanced efficiency in translation. E. coli strain HB101 containing the plasmid Nco5AHSODm was deposited at the A.T.C.C. on Oct. 3, 1986 and given Accession No. 67191.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.