Methods for reducing ischemic injury of the heart via the sequential administration of monophosphoryl lipid A and adenosine receptor agents

US6329349A · kind A · utility

Assignees

• The Trustees of the University of Pennsylvania · US
• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Bruce Liang · Avon, US
• Kenneth A. Jacobson · Silver Spring, US

Key dates

• Filing date: Apr 24, 2000
• Grant date: Dec 11, 2001
• Expiry date: Apr 24, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K45/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Materials and methods for reducing or preventing ischemic damage of the heart are disclosed. A preferred embodiment of the invention comprises methods of sequential administration of a plurality of cardioprotective agents to patients suffering from ischernic damage or at risk for the same.