Pyrazolo-pyridine derivatives as ligands for GABA receptors
US6333336A · kind A · utility
2Cited by
3References
10Claims
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Key dates
| Filing date | Aug 23, 2000 |
| Grant date | Dec 25, 2001 |
| Priority date | — |
| Expiry date | Aug 23, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pyrazolo[4,3-c]pyridin-3-one derivatives substituted at the 2-position by an optionally substituted aryl or heteroaryl moiety, and having pendant substituents at the 7-position and optionally also at the 6-position, are selective ligands for GABA.sub.A receptors, particularly having high affinity for the .alpha.2 and/or .alpha.3 subunit, and are useful in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.