Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
US6344321B1 · kind B1 · utility
23Cited by
8References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 29, 1999 |
| Grant date | Feb 5, 2002 |
| Priority date | — |
| Expiry date | Jul 29, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4753
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides nucleic acid ligands to hepatocyte growth factor/scatter factor (HGF) and its receptor c-met. The nucleic acid ligands of the instant invention are isolated using the SELEX method. SELEX is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the invention are useful as diagnostic and therapeutic agents for diseases in which elevated HGF and c-met activity are causative factors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.