Nucleic acid immunization using a virus-based infection/transfection system
US6355247B1 · kind B1 · utility
9Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 4, 1996 |
| Grant date | Mar 12, 2002 |
| Priority date | — |
| Expiry date | Nov 4, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/24222
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for nucleic acid immunization which results in a cell-mediated immunological response to a selected antigen is disclosed. The method utilizes the T7 RNA infection/transfection system which provides for the controlled, transient cytoplasmic expression of a given antigen and which elicits the production of class I MHC restricted CTLs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.