Multiplexing methods for identifying nucleic acids using denaturing liquid chromatography
US6379889B1 · kind B1 · utility
5Cited by
7References
19Claims
0Family size
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Key dates
| Filing date | Nov 4, 1999 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Nov 4, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method is provided for the separation of nucleic acid samples. The method includes: providing a test mixture of a plurality of nucleic acid samples, wherein each sample is labeled with a spectrally detectable tag; applying the test mixture to a reversed phase solid support; eluting the mixture under partially denaturing conditions; and detecting spectrally resolved signals produced by the nucleic acid samples labeled with the detectable tags.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.