Chromatography cartridge end cap fixation
US6398953B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 5, 2000 |
| Grant date | Jun 4, 2002 |
| Priority date | — |
| Expiry date | Jun 5, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/6052
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of forming a chromatography cartridge includes providing a flexible-walled tube, placing a first end cap within the tube in sealing engagement with the tube wall, forming a media bed within the tube supported by the first end cap, cooling a second end cap to thermally contract the second end cap, placing the contracted second end cap within the tube and against the media bed, and sealing the second end cap to the tube wall by thermal expansion of the second end cap upon warming. The expansion of the second end cap causes the tube wall to deform. A chromatography column includes a flexible-walled tube containing chromatography media, and an end cap positioned within the tube. The end cap has a dimension greater than an inner dimension of the tube such that the tube is locally deformed by the end cap.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.