Process for preparing aryl-iminomethyl-carbamino acid esters

US6417382B1 · kind B1 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Joerg Brandenburg · Ingelheim am Rhein, DE
• Rolf Schmid · Gelterkinden, CH
• Rainer Soyka · Biberach, DE
• Ralf Anderskewitz · Laupheim, DE
• Rolf Bauer · Ingelheim am Rhein, DE
• Rainer Hamm · Ingelheim am Rhein, DE
• Jutta Kroeber · Bingen, DE

Key dates

• Filing date: Jan 9, 2001
• Grant date: Jul 9, 2002
• Expiry date: Jan 9, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C271/64
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a process suitable for large-scale industrial use for preparing compounds of general formula (I) wherein:R1 denotes a group selected from among methyl, ethyl, propyl, cyclopentyl, cyclohexyl, phenyl, benzyl and —C(Me2)phenyl, each of which is optionally mono-, di- or trisubstituted by hydroxy; and,R2 denotes a group selected from among methyl, ethyl, propyl and benzyl.