Hybrid botulinal neurotoxins
US6444209B1 · kind B1 · utility
27Cited by
1References
5Claims
0Family size
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Key dates
| Filing date | Nov 3, 2000 |
| Grant date | Sep 3, 2002 |
| Priority date | — |
| Expiry date | Nov 3, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A hybrid botulinal neurotoxin is disclosed. In one embodiment, the neurotoxin comprises a combination of a botulinal neurotoxin heavy chain and light chain, wherein the light chain and heavy chain are not of the same serotype and wherein the heavy and light chains are linked by a homobifunctional sulfydryl linker. A method for creating hybrid neurotoxins comprised of different functional domains is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.