FldA gene and methods for detecting predisposition to mucosa-associated lymphoid tissue lymphoma of the stomach
US6451533B1 · kind B1 · utility
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3Claims
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Key dates
| Filing date | Mar 9, 2000 |
| Grant date | Sep 17, 2002 |
| Priority date | — |
| Expiry date | Mar 9, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a Helicobacter pylori gene, fldA, a putative flavodoxin gene and whose expression is associated with mucosa-associated lymphoid tissue lymphoma of the stomach (MALToma). A G insertion at position 481 of the fldA gene was more frequently observed in strains associated with MALToma than other strains. Therefore, the present invention provides a new method to identify H. pylori patient with higher risk of developing gastric MALToma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.