Glycopeptide derivatives and pharmaceutical compositions containing the same

US6455669B1 · kind B1 · utility

Assignee

• Theravance, Inc. · US

Inventors

• J. Kevin Judice · El Granada, US
• Paul R. Fatheree · San Francisco, US
• Bernice M. T. Lam · San Francisco, US
• Michael R. Leadbetter · Fremont, US
• Martin S. Linsell · San Mateo, US
• YongQi Mu · Los Altos, US
• Sean G. Trapp · San Francisco, US
• Guang Yang · Nanhu, CN
• Yan Zhu · Beijing, CN

Key dates

• Filing date: Nov 1, 2000
• Grant date: Sep 24, 2002
• Expiry date: Nov 1, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula:—Ra—Y—Rb—(Z)xwhere Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.