Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates

US6475486B1 · kind B1 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Cenek Kolar · Marburg, DE
• Jorg Czech · Marburg, DE
• Klaus Bosslet · Marburg, DE
• Gerhard Seemann · Lahntal, DE
• Hans-Harald Sedlacek · Marburg, DE
• Dieter Hoffman · Marburg, DE

Key dates

• Filing date: Jun 30, 1999
• Grant date: Nov 5, 2002
• Expiry date: Jun 30, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to glycosyl-etoposide prodrugs, a process for the preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates for treating cancers.