Sodium channel drugs and uses

US6479498B1 · kind B1 · utility

Assignee

• Theravance, Inc. · US

Inventors

• Daniel Marquess · Rue de l'Église, US
• Seok-Ki Choi · Ann Arbor, US
• David T. Beattie · Belmont, US
• John H. Griffin · Atherton, US
• Scott A. Armstrong · Angleton, US
• Timothy J. Church · San Mateo, US
• Thomas E. Jenkins · Louisville, US
• David C. Green · Pacifica, US

Key dates

• Filing date: Nov 9, 2001
• Grant date: Nov 12, 2002
• Expiry date: Nov 9, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The compounds of this invention comprise 2-10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Na+ channel, thereby modulating the biological activities thereof.