Vitronectin receptor antagonists, their preparation and their use

US6482821B2 · kind B2 · utility

Assignees

• Hoechst GmbH · DE
• Genentech, Inc. · US

Inventors

• Volkmar Wehner · Bischofsheim a.d.Rhön, DE
• Hans Ulrich Stilz · Frankfurt am Main, DE
• Anuschirwan Peyman · Kelkheim, DE
• Karlheinz Scheunemann · Liederbach, DE
• Jean-Marie Ruxer · Paris, FR
• Denis Carniato · Marcoussis, FR
• Jean-Michel Lefrancois · Livry-Gargan, FR
• Thomas Gadek · Oakland, US
• Robert McDowell · San Francisco, US

Key dates

• Filing date: Feb 8, 2001
• Grant date: Nov 19, 2002
• Expiry date: Feb 8, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D243/24
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Vitronectin receptor antagonists, their preparation and their use The present invention relates to compounds of the formula I,A—B—D—E—F—G   (I) in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.