Substituted heterocyclic siprodecane compound active as an antagonist of neurokinin 1 receptor

US6482829B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Guido Galley · Rheinfelden (Baden), DE
• Thierry Godel · Basel, CH
• Annick Goergler · Basel, CH
• Torsten Hoffmann · Weil am Rhein, DE
• Sabine Kolczewski · Lörrach, DE
• Stephan Roever · Inzlingen, DE

Key dates

• Filing date: May 21, 2001
• Grant date: Nov 19, 2002
• Expiry date: May 21, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of the formula as described herein and pharmaceutically acceptable acid addition salts thereof. The described compounds have a good affinity to the NK1 receptor.