Engulfment gene and uses thereof
US6489454B1 · kind B1 · utility
0Cited by
2References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 11, 1998 |
| Grant date | Dec 3, 2002 |
| Priority date | — |
| Expiry date | Jun 11, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2217/05
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a signal transduction pathway which promotes phagocytosis of apoptotic cells and in particular relates to a protein known as CED-6 in the nematode worm C. elegans, human equivalents of CED-6 protein and nucleic acids encoding them. The invention also relates to use of the proteins and encoding nucleic acids in assay methods for detecting compounds which enhance or inhibit the signal transduction pathway and use of the proteins, nucleic acids and identified enhancer or inhibitor compounds in methods of treatment of human or animal disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.