Patent assignee · US · COMPANY

Cold Spring Harbor Laboratory

193Patents
85Active
193Granted
51Portfolio score

Filing activity: Jun 23, 1975 → Aug 4, 2023 · 25 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US5565324A Complex combinatorial chemical libraries encoded with tags Chemistry; Metallurgy 342 Expired
US9404156B2 Varietal counting of nucleic acids for obtaining genomic copy number information Chemistry; Metallurgy 208 Active
US5977305A Cloning by complementation and related processes Chemistry; Metallurgy 203 Expired
US6100025A Cloning by complementation and related processes Chemistry; Metallurgy 198 Expired
US5701256A Method and apparatus for biological sequence comparison Physics 133 Expired
US5721099A Complex combinatorial chemical libraries encoded with tags Chemistry; Metallurgy 115 Expired
US6255071A Mammalian viral vectors and their uses Chemistry; Metallurgy 78 Expired
US5041376A Method for identifying or shielding functional sites or epitopes of proteins that enter the exocytotic pathway of eukaryotic cells, the mutant proteins so produced and genes encoding said mutant proteins Chemistry; Metallurgy 73 Expired
US5789172A Methods of determining the structure of a compound encoded by identifiers having tags Chemistry; Metallurgy 72 Expired
US5436142A Methods for producing probes capable of distingushing variant genomic sequences Chemistry; Metallurgy 69 Expired
US6001579A Supports and combinatorial chemical libraries thereof encoded by non-sequencable tags Chemistry; Metallurgy 66 Expired
US6809117B2 Therapeutic uses of nitric oxide inhibitors Human Necessities 56 Expired
US7186512B2 Methods and compositions for determining methylation profiles Chemistry; Metallurgy 55 Expired
US6025192A Modified retroviral vectors Chemistry; Metallurgy 54 Expired
US5501964A Methods for producing probes capable of distinguishing DNA from related sources Chemistry; Metallurgy 52 Expired
US4035377A Slab gel electrophoresis apparatus Physics 38 Expired
US6277606A Representational approach to DNA analysis Chemistry; Metallurgy 38 Expired
US6936477B2 Complex combinatorial chemical libraries encoded with tags Physics 30 Expired
US8980853B2 Compositions and methods for modulation of SMN2 splicing in a subject Chemistry; Metallurgy 30 Active
US6037136A Interactions between RaF proto-oncogenes and CDC25 phosphatases, and uses related thereto Chemistry; Metallurgy 29 Expired
US5441880A Human cdc25 genes, encoded products and uses thereof Chemistry; Metallurgy 28 Expired
US8993532B2 Structurally designed shRNAs Chemistry; Metallurgy 27 Active
US6503759B1 Complex combinatorial chemical libraries encoded with tags Chemistry; Metallurgy 27 Expired
US7947731B2 Augmented cognitive training Human Necessities 26 Expired
US8407012B2 Methods and systems of DNA sequencing Physics 26 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.