Triazolo-pyridazine derivatives as ligands for gaba receptors
US6500828B1 · kind B1 · utility
5Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 23, 2001 |
| Grant date | Dec 31, 2002 |
| Priority date | — |
| Expiry date | Jul 23, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a difluoro-or tri-fluoro-substituted phenyl ring at the 3-position, a triazolyl moiety at the 6-position, and a tert-butyl group at the 7-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and are useful in the treatment of anxiety and convulsions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.