Antifungal compositions with improved bioavailability
US6509038B2 · kind B2 · utility
8Cited by
4References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1998 |
| Grant date | Jan 21, 2003 |
| Priority date | — |
| Expiry date | Nov 19, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.