Conjugate vaccine for Neisseria meningitidis

US6531131B1 · kind B1 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Xin Gu · San Francisco, US
• Chao-Ming Tsai · Bethesda, US

Key dates

• Filing date: Jul 26, 2000
• Grant date: Mar 11, 2003
• Expiry date: Jul 26, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2039/6037
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A conjugate vaccine for Neisseria meningitidis comprising lipooligosaccharide which does not contain a lacto-N-tetraose antigen from which at least one primary O-linked fatty acid has been removed conjugated to an immunogenic carrier. The vaccine is useful for prevention of meningitis and septic shock in mammals.