Base protecting groups and synthons for oligonucleotide synthesis
US6531589B1 · kind B1 · utility
16Cited by
5References
37Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1996 |
| Grant date | Mar 11, 2003 |
| Priority date | — |
| Expiry date | Feb 8, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides new methods for synthesizing oligonucleotides that allow for deprotection of the oligonucleotides under more mild conditions than existing methods. The invention further provides a nucleoside base protecting group that is stable under oligonucleotide synthesis conditions, but which can be removed under more mild conditions than existing protecting groups, as well as nucleoside synthons having such base protecting groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.