Methods for encapsulating plasmids in lipid bilayers
US6534484B1 · kind B1 · utility
220Cited by
14References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 1999 |
| Grant date | Mar 18, 2003 |
| Priority date | — |
| Expiry date | Nov 8, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, fully encapsulate the plasmid and are serum-stable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.