Methods and composition for lowering the level of tumor necrosis factor (TNF) in TNF-associated disorders
US6537540B1 · kind B1 · utility
50Cited by
28References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 2000 |
| Grant date | Mar 25, 2003 |
| Priority date | — |
| Expiry date | May 26, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides recombinant adeno-associated virus (rAAV) vectors encoding a tumor necrosis factor (TNF) antagonist and methods using these vectors to reduce levels of TNF in a mammal. The invention also provides methods of using these rAAV vectors in palliating TNF-associated disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.