Patent assignee · US · COMPANY

Targeted Genetics Corporation

20Patents
0Active
20Granted
32Portfolio score

Filing activity: Jun 1, 1994 → Mar 31, 2004

Most-cited patents

PatentTitleAreaCited byStatus
US5658776A Generation of high titers of recombinant AAV vectors Chemistry; Metallurgy 193 Expired
US6566118B1 Methods for generating high titer helper-free preparations of released recombinant AAV vectors Chemistry; Metallurgy 160 Expired
US6596535B1 Metabolically activated recombinant viral vectors and methods for the preparation and use Chemistry; Metallurgy 137 Expired
US7125717B2 Metabolically activated recombinant viral vectors and methods for their preparation and use Chemistry; Metallurgy 119 Expired
US6995006B2 Methods for generating high titer helper-free preparations of released recombinant AAV vectors Chemistry; Metallurgy 69 Expired
US6989264B2 Methods for generating high titer helper-free preparations of released recombinant AAV vectors Chemistry; Metallurgy 63 Expired
US6642051B1 Amplifiable adeno-associated virus(AAV) packaging cassettes for the production of recombinant AAV vectors Chemistry; Metallurgy 56 Expired
US6537540B1 Methods and composition for lowering the level of tumor necrosis factor (TNF) in TNF-associated disorders Chemistry; Metallurgy 50 Expired
US6083751A Chimeric receptors for the generation of selectively-activatable TH-independent cytotoxic T cells Chemistry; Metallurgy 41 Expired
US5736387A Envelope fusion vectors for use in gene delivery Chemistry; Metallurgy 34 Expired
US6008202A Stable lipid-comprising drug delivery complexes and methods for their production Human Necessities 32 Expired
US6924128B2 Packaging cell lines for generation of high titers of recombinant AAV vectors Chemistry; Metallurgy 29 Expired
US6893865B1 Methods, compositions, and cells for encapsidating recombinant vectors in AAV particles Chemistry; Metallurgy 26 Expired
US6936466B2 Transcriptionally-activated AAV inverted terminal repeats (ITRs) for use with recombinant AAV vectors Chemistry; Metallurgy 25 Expired
US6316257A "Modified rapid expansion methods (""modified-REM"") for in vitro propagation of T lymphocytes" Chemistry; Metallurgy 23 Expired
US6541258B2 AAV split-packaging genes and cell lines comprising such genes for use in the production of recombinant AAV vectors Chemistry; Metallurgy 17 Expired
US5874556A Hybrid genes for use in the production of T.sub.H -independent cytotoxic T cells Chemistry; Metallurgy 10 Expired
US6346415B1 Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors Chemistry; Metallurgy 10 Expired
US7749491B2 Compounds and methods to enhance rAAV transduction Chemistry; Metallurgy 9 Expired
US6593124B1 Hybrid genes for expression of stimulatory factors in activated T cells Chemistry; Metallurgy 0 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.