Polypeptides having kinase activity

US6541232B1 · kind B1 · utility

Assignee

• IMMUNEX CORPORATION · US

Inventors

• John E. Sims · Seattle, US
• G. Duke Virca · Bellevue, US
• Timothy Bird · Bainbridge Island, US
• Dirk M. Anderson · Seattle, US

Key dates

• Filing date: Apr 7, 2000
• Grant date: Apr 1, 2003
• Expiry date: Apr 7, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/1205
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Purified and isolated IL-1/TNF-&agr;-activated kinase (ITAK), nucleic acids encoding ITAK, processes for production of recombinant forms of ITAK, pharmaceutical compositions containing ITAK, and use of ITAK in therapies and in various assays, including assays to detect antagonists and agonists of ITAK are provided.