Acridone-derived compounds useful as antineoplastic and antiretroviral agents
US6541483B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 15, 2001 |
| Grant date | Apr 1, 2003 |
| Priority date | — |
| Expiry date | Mar 18, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to several novel acridone-derived compounds of of formula (I) or (II). These compounds are potent anti-viral agents, useful in the treatment of viral diseases, such as Human Immunodeficiency Virus. In addition, these compounds are anti-neoplastic agents useful in the treatment of various forms of cancer. wherein R1 and R2 are independently —H, —OH, amino, alkylamino, dialkylamino, alkoxy, alkyl, haloalkyl or halogen; n is 2 to 6, X and X′ are independently —N or —NO2; Y and Y′ are independently —N or —CH, or —H; and the double-slash represents a double bond or no bond.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.